ACTUALITAT

Carmen Claver

 

The Board of the Société Chimique de France, during its meeting on June 23 2016, decided to award to Carmen Claver, the Scientific director of CTQC, with the 2016 SCF French-Spanish “Miguel Catalán - Paul Sabatier” Prize in recognition of his eminent works in homogeneous catalysis chemistry, especially for his discoveries in asymetric hydroformylation reactions and in nanoparticles catalysts for the Fischer Tropsch reactions.

It is also in recognition of the strong links that Carmen Claver established with the French chemists.

Direct Quantification of DNA Base Composition by Surface-Enhanced Raman Scattering Spectroscopy

DNA BASE COMPOSITION


Judit Morla-Folch, Ramon A. Alvarez-Puebla, and Luca Guerrini
J. Phys. Chem. Lett., 2016, 7, pp 3037–3041- DOI: 10.1021/acs.jpclett.6b01424

Abstract: Design of ultrasensitive DNA sensors based on the unique physical properties of plasmonic nanostructures has become one of the most exciting areas in nanomedicine. However, despite the vast number of proposed applications, the determination of the base composition in nucleic acids, a fundamental parameter in genomic analyses and taxonomic classification, is still restricted to time-consuming and poorly sensitive conventional methods. Herein, we demonstrate the possibility of determining the base composition in single- and double-stranded DNA by using a simple, low-cost, high-throughput, and label-free surface-enhanced Raman scattering (SERS) method in combination with cationic nanoparticles

Ultrasensitive multiplex optical quantification of bacteria in large samples of biofluids

Ultrasensitive multiplex optical

N. Pazos-Perez, E. Pazos, C. Catala, B. Mir-Simon, S. Gómez-de Pedro, J. Sagales, C. Villanueva, J.Vila, A.Soriano, F. J. García de Abajo & R. A. Alvarez-Puebla
Scientific Reports 6:29014- DOI: 10.1038/srep29014

Abstract:
Efficient treatments in bacterial infections require the fast and accurate recognition of pathogens, with concentrations as low as one per milliliter in the case of septicemia. Detecting and quantifying bacteria in such low concentrations is challenging and typically demands cultures of large samples of blood (~1 milliliter) extending over 24–72 hours. This delay seriously compromises the health of patients. Here we demonstrate a fast microorganism optical detection system for the exhaustive identification and quantification of pathogens in volumes of biofluids with clinical relevance (~1 milliliter) in minutes. We drive each type of bacteria to accumulate antibody functionalized SERS-labelled silver nanoparticles. Particle aggregation on the bacteria membranes renders dense arrays of inter-particle gaps in which the Raman signal is exponentially amplified by several orders of magnitude relative to the dispersed particles. This enables a multiplex identification of the microorganisms through the molecule-specific spectral fingerprints.

EN QUÈ ET PODEM AJUDAR ?

 

ris3cat
 
 ACCIÓ posa en marxa noves convocatòries d'ajuts per impulsar la innovació i la incorporació de tecnologia a les empreses catalanes. La nova política d'innovació de la Generalitat de Catalunya destinarà més de 103 milions d'euros a projectes d'innovació d'empreses catalanes en el període 2015-2020.